★★★★★RATED 4.9 BY 360,000+ HAPPY CUSTOMERS

The #1 Dentist Recommended
Nano-hydroxyapatite Toothpaste

  • Science-BackedClinically validated at University of Toronto
  • Fluoride-Free10% premium Nano-hydroxyapatite + advanced peptides
  • Dentist-DevelopedCleaner ingredients you can trust
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Get the Welcome Kit Free

Welcome kit - 1 Eggshell Mango Toothpaste
included on your first order

  • Derived from eggshellsClinically validated at University of Toronto
  • 10% nHAp concentrationthe level the science actually calls for
  • Dentist-DevelopedCleaner ingredients you can trust
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Complete Your Oral Care Routine

Introducing Dr. Jen’s Wellness Pre-Rinse™

Dr. Jen's Mouth Rinse.
The Missing Piece.

Premium Nanohydroxyapatite with aloe vera and calendula for healthier enamel and gums.

  • Prepares Your Mouth for BrushingDesigned to prime your oral environment before you brush
  • Supports Healthier GumsAloe vera and calendula to calm and nourish gum tissues.
  • Alcohol-Free, Cleaner IngredientsWellness Pre-Rinse delivers a gentle, nature-inspired approach to oral care
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Introducing Fluoride-Free KERAHAP™

The Next Evolution of
Nano-Hydroxyapatite Technology

Inspired by Nature Peptide Enhanced Nano-Hydroxyapatite Technology

Dr. Jen just created the first polypeptide nano-hydroxyapatite toothpaste. The most advanced toothpaste in the world that combines Biomimetic Peptides with Premium nHAp that helps with:

  • Mimicing Natural Mineral Formation
  • Supporting Enhanced Remineralization
  • Enamel Protection
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Dentist Founded
Dentist Founded
Trusted by 500+ dentists nationwide
Trusted by 500+ dentists nationwide
Family Owned
Family Owned
Independent Company
Independent Company
Research Driven
Research Driven
30-day Smile guarantee
30-day Smile guarantee
Premium-Grade NHAp Crystals
Premium-Grade NHAp Crystals

Personalize Your Oral Care

Your mouth is unique. Different concerns, different needs, from sensitivity to gum support to orthodontic care. Just like skincare, personalized oral care means better results for your specific smile.

Fluoride Toothpaste
Fluoride-Free Toothpastes
Fluoride ToothpasteFluoride Best Seller
Fluoride ToothpasteFluoride Best Seller

Original Super Paste - Triple Protection toothpaste

  • For high cavity risk or cavity history
  • For dry mouth support (xerostomia)
  • Replaces 5000 ppm fluoride
Flavor: Cool Mint Strawberry
$26.00
Learn More
Fluoride-Free TootpasteNEW!
Fluoride-Free TootpasteNEW!

Dr. Jen's KeraHAp™

  • First Peptide-Enhanced premium nHAp toothpaste
  • Support Biomimetic Enamel Repair
  • Mimics Natural Mineral Formation
Flavor: Cool Mint
$28.00
Learn More
Fluoride Toothpaste
Fluoride Toothpaste

Super Paste Perio™

  • Low RDA
  • Sensitive roots
  • Periodontal patients
$28.00
Learn More
Fluoride-Free TootpasteFluoride-Free Best Seller
Fluoride-Free TootpasteFluoride-Free Best Seller

1st and Only Naturally Derived Eggshell nHAp

  • Fluoride-free preference
  • Supports mineral uptake
  • Cleaner ingredients and a formulation that follows the science
  • Allergen warning: This product contains Eggshell
Flavor: Cool Mint Orange Mango
$22.00
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Fluoride Toothpaste
Fluoride Toothpaste

Super Paste Ortho™

  • Orthodontic patients
  • White spot lesion prevention
  • Aligner ann braces patients
Flavor: Cool Mint
$28.00
Learn More
Fluoride-Free Toothpaste
Fluoride-Free Toothpaste

Fluoride-Free Premium nHAp Toothpaste

  • Fluoride-free preference
  • Cleaner ingredients & transparent formula
  • Premium nHAP crystals
Flavor: Cool Mint Strawberry Watermelon
$18.50
Learn More
Fluoride ToothpasteFluoride Best Seller
Fluoride ToothpasteFluoride Best Seller

Original Super Paste - Triple Protection toothpaste

  • For high cavity risk or cavity history
  • For dry mouth support (xerostomia)
  • Replaces 5000 ppm fluoride
Flavor: Cool Mint Strawberry
$26.00
Learn More
Fluoride Toothpaste
Fluoride Toothpaste

Super Paste Perio™

  • Low RDA
  • Sensitive roots
  • Periodontal patients
$28.00
Learn More
Fluoride Toothpaste
Fluoride Toothpaste

Super Paste Ortho™

  • Orthodontic patients
  • White spot lesion prevention
  • Aligner ann braces patients
Flavor: Cool Mint
$28.00
Learn More
Fluoride-Free TootpasteNEW!
Fluoride-Free TootpasteNEW!

Dr. Jen's KeraHAp™

  • First Peptide-Enhanced premium nHAp toothpaste
  • Support Biomimetic Enamel Repair
  • Mimics Natural Mineral Formation
Flavor: Cool Mint
$28.00
Learn More
Fluoride-Free TootpasteFluoride-Free Best Seller
Fluoride-Free TootpasteFluoride-Free Best Seller

1st and Only Naturally Derived Eggshell nHAp

  • Fluoride-free preference
  • Supports mineral uptake
  • Cleaner ingredients and a formulation that follows the science
  • Allergen warning: This product contains Eggshell
Flavor: Cool Mint Orange Mango
$22.00
Learn More
Fluoride-FreeOptimal 10% nHAp
Fluoride-FreeOptimal 10% nHAp

Fluoride-Free Premium nHAp Toothpaste

  • Fluoride-free preference
  • Cleaner ingredients & transparent formula
  • Premium nHAP crystals
Flavor: Cool Mint Strawberry Watermelon
$18.50
Learn More
10% nHApAlcohol-FreeNEW!
10% nHApAlcohol-FreeNEW!

Dr. Jen's Mouth Rinse

Wellness Pre-Rinse

  • Prepares your mouth before brushing
  • Aloe vera and calendula for gum support
  • Alcohol-free, cleaner ingredients
Flavor: Cool Mint
$28.00
Learn More
Plastic-Free
Plastic-Free

100% Italian Silk Floss Infused with Nanohydroxyapatite

  • Made with premium 100% Italian Silk
  • Gentle on the gums
  • Effective at removing plaque
Flavor: Papaya Mint Black Cherry
$8.00
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Xylitol
Xylitol

Dry Mouth Gel

  • 10% premium Nanohydroxyapatite
  • Soothing relief for dry mouth
  • Cleaner ingredients
$16.00
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Toothbrush
Toothbrush

Advanced Gentle Bristle Toothbrush

  • Innovative dense bristle head
  • Gentle Cleaning Experience
  • Helps protect tooth enamel and gums
$8.50
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Who is actually behind your toothpaste?

Powered by Nature, Rooted in Science

Dr. Jen's customized formulas solve unique patient needs, unlike one-size-fits-all, mass- produced toothpaste.

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Powered by Nature, Rooted in Science

DR. JEN'S TOOTHPASTES

GENERIC HYDROXYAPATITE TOOTHPASTES

Independent Dental Family-Owned Brand

Venture Capitalist and Investment Banker Formulas

Formulated for Enamel Health

Mass Produced for Maximum Profit

Backed by Science

Driven by Marketing and Social Media Trends

Customized Formulas for Individual Needs

Generic, One Size Fits All Formulations

The Dr.Jen Difference: Premium-Grade NHAp

Mineral Uptake
Calcium And Phosphate

Low-Grade nHAp

Low-Grade
nHAp

Premium Grade nHAp

Premium Grade nHAp

Premium-grade Nanohydroxyapatite is proven to deliver optimal levels of protection and hypersensitivity management. Link to study.

While cheaper formulations source lower grade Nanohydroxyapatite, Dr. Jen's sources premium grade Nanohydroxyapatite for higher performance.

Low-Grade nHApLow-Grade
nHAp
Premium-Grade nHApPremium-Grade nHAp

Not All Nano-Hydroxyapatite is Create Equal

The quality, purity, and crystal structure of nHAp directly impact biocompatibility, safety, and remineralization.

LOW-GRADE
nHAp LARGER PARTICLES • IRREGULAR • LOWER PURITY
LOW-GRADE
nHAp
  • Irregular shapes and sizes
  • Larger particle size
  • Lower purity with more impurities
  • Inconsistent performance
  • Lower biocompatibility
  • Less effective remineralization
MID-RANGE 
nHAp MIXED SHAPES • MODERATE PURITY
MID-RANGE 
nHAp
  • Medium particle size
  • Moderate purity
  • Mixed shapes (spheres, plates, short rods)
  • Variable consistency
  • Moderate biocompatibility
  • Moderate remineralization potential
PREMIUM PHARMACEUTICAL
GRADE nHAp ROD-SHAPED • NANO-SIZED • ULTRA-PURE
PREMIUM PHARMACEUTICAL
GRADE nHAp
  • Uniform rod-shaped crystals
  • Ultra-high purity
  • Nano-sized for optimal absorption
  • High biocompatibility
  • Consistent, reliable performance
  • Superior remineralization and protection

Supports a healthier oral microbiome

Enriched With Soothing Botanicals

Anise Extract

Anise Extract Illicium verum

Helps inhibit odor-causing bacteria and support oral microbiome balance.

Papaya Extract

Papaya Extract Carica papaya

Support healing in mild gingivitis environments

Black Cherry Extract

Black Cherry Extract Prunus Serotina

Antioxidant-rich extract that supports gum health and protects oral tissues.

Spearmint

Spearmint Mentha Spicata

Provides natural antibacterial activity while maintain oral freshness.

Peppermint

Peppermint Mentha Arvensis

Naturally antibacterial mint that helps reduce odor-causing bacteria. 

Stevia Rebaudiana 
Leaf Extract

Stevia Rebaudiana 
Leaf Extract Illicium verum

Sweetens naturally without synthetic sugars or artificial sweeteners.

Chinese Licorice
Root Extract

Chinese Licorice
Root Extract Glycyrrhiza Uralensis

Supports gum health with soothing anti-inflammatory properties.

The problem
The solution
The mission

It started with a phone call no parent wants

Dr. Jen's daughter, months from starting dental school and following in her mother's footsteps, developed an infection from a fractured tooth. The treatment that followed set off a chain of complications that landed her in the hospital and put her dream on hold for two years.

When she finally came home to recover, doctors gave Dr. Jen one clear instruction: look at every product the family used, down to the toothpaste.

The expert behind the formula

Top of her class, University of Minnesota School of Dentistry, 1994
University of Minnesota Department of Orthodontics
The problem
The solution
The mission

So Dr. Jen made one herself

As a dentist, and an engineer before that, she wanted a toothpaste clean enough to feel good about, and serious about caring for teeth. She couldn't find one that did both. So she started making it in her own kitchen.

That kitchen experiment became seven years of work alongside some of the world's leading toothpaste chemists, formulating with Nanohydroxyapatite, an ingredient widely used in toothpaste across Japan and Europe.

A Career Built on Excellence

MN Association of Orthodontic Achievement Award
In private practice since 1996 · mother of three
The problem
The solution
The mission

A kitchen experiment that dentists came looking for

Dr. Jen never set out to build a brand. But once the toothpaste was online, dentists across the country started calling, using it for their own families, then asking to bring it to their patients.

That's the standard the brand still holds to: make the toothpaste she'd put in her own daughter's hands.

“I searched health food stores and the internet for a toothpaste with proven ingredients, and came up empty-handed. So I created it.”

— Dr. Jennifer Eisenhuth, DDS

Feel the Difference

Try Dr. Jen risk-free for 30 days. If you're not completely satisfied, we'll refund your purchase, no questions asked.

  • Smile guarantee

  • No questions asked

  • Trusted by 500+ dentists nationwide

Making the switch from fluoride can feel like a big step, but we're confident that once you feel the difference, you won't want to go back.

IN OUR CUSTOMERS' WORDS

John Doe

I love this toothpaste. My teeth are doing so much better at the gum line. I just bought an extra one for my son

Sherry

Good taste. 

Very good cleaning.

Matt

3rd time I have gotten this! Love tem

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Not sure which Dr Jen Toothpaste is right for you?

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Frequently Asked Questions

Dr. Jen's is the #1 dentist-recommended Nanohydroxyapatite toothpaste, trusted by dental professionals nationwide. Dr. Jen has spent six years perfecting these advanced formulations, sourcing the highest-grade Nanohydroxyapatite available. Our rod-shaped crystals meet rigorous EU safety standards for synthetic nHAp, and our eggshell nHAp is ISO certified. While other brands have approached us wanting to use our premium sources, we protect the integrity of our supply chain to ensure every tube meets our exacting standards.

Dr. Jen Super Paste combines 10% premium Nanohydroxyapatite with fluoride, clinically proven to outperform fluoride-only toothpastes. This triple-action formula uses Nanohydroxyapatite, fluoride, and xylitol to keep enamel strong and resilient. Available in Mint and Strawberry.
Dr. Jen Fluoride-Free delivers the same cavity protection as fluoride using premium-grade Nanohydroxyapatite at the optimal 10% concentration. Blended with our proprietary essential oils to support a healthy oral microbiome. Available in Mint and Strawberry.
Dr. Jen Eggshell is the first and only naturally-derived nHAp toothpaste, formulated with 10% premium eggshell Nanohydroxyapatite. Eggshells naturally contain magnesium and zinc, which promote higher mineral uptake for enhanced enamel protection. Available in Mint and Orange Mango.

We use a proprietary blend of essential oils, no synthetic flavoring. Our mint paste contains essential oils with coconut oil-based foaming, while our strawberry paste is naturally foam-free. You'll never find sodium lauryl sulfate (SLS) in any Dr. Jen's formula.

Nanohydroxyapatite (nHAp) is composed of calcium and phosphate minerals, the same minerals that make up 97% of your tooth enamel and the mineral portion of your bones. The "nano" means the particles are extremely small, measured in nanometers, allowing them to behave like your enamel crystals.

How it works:

  • Absorbs and removes dental plaque
  • Replenishes lost calcium and phosphate minerals
  • Fills in micro-fissures on tooth surfaces
  • Reduces sensitivity by sealing exposed dentinal tubules
  • Think of it as giving your teeth the building blocks they need to stay strong.

There's something we want you to know because behind every tube is a story that started long before it reached your bathroom shelf.

It began in a hospital room.

Years ago, Dr. Jen's daughter became dangerously ill with a life-threatening stomach condition. As any parent would, Dr. Jen searched for every way to support her daughter's healing, down to the smallest details, including something as simple as toothpaste.

What she discovered shocked her.

Fluoride-free toothpastes aren't regulated. Brands can claim "nanohydroxyapatite" while using cheap, low-quality versions or including so little that it does almost nothing. Labels didn't tell the full truth, and Dr. Jen couldn't find a single toothpaste that matched what the science said her daughter needed.

In that hospital room, one thing became clear: if the right toothpaste didn't exist, she would have to create it.

A mother's worry became a mission.

Dr. Jen spent years studying particle size, purity, concentration, safety, and biocompatibility. She rejected anything that didn't meet the highest standard, even when it cost more.

Only true high-grade nanohydroxyapatite
Only the optimal concentration proven to protect enamel
Only clean, gut-friendly ingredients gentle enough for someone fighting for their health
No shortcuts. No compromises. Just a formula built with the same care she wanted for her own child.

That's why our toothpaste costs more. Because it was never created to be the cheapest. It was created to be the safest, the purest, and the most effective. Born from fear, love, science, and the determination of a mother who refused to settle.

And yet, it comes down to 25 cents a day.

For up to 25 cents per day, you give your enamel the level of protection research actually supports, without the gut-disrupting ingredients found in many conventional formulas. About the same as your morning coffee, but for your long-term health.

Brush as you normally would, then spit out the excess but don't rinse. For maximum mineral uptake, wait 30 minutes before eating or drinking. This allows the Nanohydroxyapatite to fully bond with your enamel. As always, discuss any specific questions or concerns with your dental team, who knows your personal oral health best.

Learn More About Oral Care

5 Surprising Facts About Flossing

LEARN MORE

Are You Making These Common Mistakes When Brushing Your Teeth?

LEARN MORE

Making At-Home Oral Healthcare Accessible to All

LEARN MORE

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YOUR REWARDS JOURNEY

1

Order 1

15% OFF + Free Welcome Kit

Order 2

Perks keep going

FREE

Order 3

Free Mouth Rinse